This calming treat helps my one-year-old settle before bed - now he sleeps through the night.
Why Pet Owners Trust ivvi
Smart insights meet heartfelt care. Join thousands of pet parents who rely on ivvi every day.
Relax
Cats
$29.90
A calmer cat often starts with steady daily support.
STEPHANIE HEINZ (VETERINARIAN)
Half a sachet keeps my cat chill, and he loves the tube. Best purchase I've made.
My Bengal stopped peeing on the bed once she started getting one calming sachet every evening.
Definitely helped calm my cat's anxiety - and they love the flavor of it.
Our rogue kitty suddenly started fussing with the others; we tried everything, and this finally took the edge off.
L-Tryptophan
The natural amino-acid building block your cat's body uses to make serotonin — the “feel-calm” neurotransmitter — supporting a relaxed, balanced mood.
Chamomile
Traditionally used to support a sense of calm and relaxation, chamomile's natural compound apigenin gently engages your cat's own calming (GABA) pathway.
Casein (alpha-Casozepine)
Our headline calming active — a natural milk-protein peptide shown in cats to help them stay relaxed and cope with stressful moments, calm but not sedated.
Magnesium
An essential mineral that supports normal nerve and muscle function — part of the foundation a calm, balanced nervous system relies on.
Vitamin B Complex
Essential cofactors your cat's body uses to make calming neurotransmitters like serotonin — and to keep her nervous system working normally.
Salmon Oil
Rich in omega-3 EPA & DHA, the brain-and-nerve fats that support normal brain and nervous-system function.
🩺
From our veterinarian
A vet's take on feline calm
The cats I worry about most aren't the loud ones — they're the ones who quietly stop being themselves.
So much of a cat's stress hides in plain sight. Cats are wired to mask discomfort, so anxiety rarely looks like “anxiety” — it looks like a cat who suddenly hides all day, hisses when you reach for her, grooms one spot raw, or stops using her litter box. Usually it traces back to a change in her world: a move, a new baby or pet, houseguests, fireworks, or the carrier-and-car ordeal of a vet visit.
My goal with an anxious cat is simple: help her feel safe again, without dimming who she is. That's why I like nutritional calming support as a gentle first step alongside the things that matter most — a predictable routine, safe hiding spots, and vertical space she can call her own.
The two calming ingredients with the most convincing feline research are alpha-casozepine — a natural milk-protein peptide that gently supports the brain's own calming (GABA) pathway — and L-tryptophan, the building block her body uses to make serotonin. They work with her physiology rather than overriding it, so she stays relaxed but still herself: calm, not sedated.
And honestly, the format matters as much as the formula. A calming supplement only works if your cat will eat it — a daily pill you have to force does its own kind of harm to a stressed cat. A creamy treat she looks forward to turns “medicine” into a moment of connection.
That combination — the best-evidenced calming actives, in a real-tuna lickable cats actually enjoy — is exactly why I'm comfortable recommending ivvi Relax.
🐾
Stephanie Heinz · Veterinarian
1. Alpha-casozepine helps cats stay calm
Beata et al., 2007 – In a controlled trial in anxious cats, the natural milk-protein peptide alpha-casozepine (the molecule behind Zylkene) improved anxiety scores — direct feline evidence for gentle, short-term calming support.
2. Coping support at the vet
Makawey, Iben & Palme, 2020 – A randomized, placebo-controlled study in 60 cats found alpha-casozepine reduced an autonomic sign of stress during veterinary visits, leading the authors to conclude it “may improve the coping of cats with stressful events.”
3. A casozepine + L-tryptophan diet eases anxiety in new situations
Landsberg et al., 2017 – In fearful cats, a diet supplemented with alpha-casozepine and L-tryptophan reduced the anxiety response to an unfamiliar environment — supporting these two actives as the calming core of the formula.
4. Tryptophan and the serotonin “calm” pathway
Hartvig et al., 1995 / DeNapoli et al., 2000 – L-Tryptophan is the dietary precursor of serotonin; supplying it (with its vitamin-B6 cofactor) supports the brain's own production of the neurotransmitter behind a calm, balanced mood.
5. How chamomile supports calm
Viola et al., 1995 / Avallone et al., 2000 – Chamomile's natural compound apigenin binds the brain's benzodiazepine (“calming”) site on the GABA-A receptor — the mechanism behind chamomile's long traditional use for relaxation.
6. Magnesium and the nervous system
Boyle et al., 2017 / Kirkland et al., 2018 – Magnesium helps regulate the excitatory NMDA receptor and supports normal nervous-system function — part of the nutritional foundation the body's own calming pathways rely on.
TRY IT RISK-FREE
PhD crafted,
vet approved
Real results
Clean, research-
backed ingredients
Built on our
exclusive base blend
The conscious choice
ivvi
Every ingredient is selected by our PhD Animal Nutritionist & vet partners
With 250,000+ 5-star reviews, the results speak for themselves
Crafted with ingredients you trust in your own routine - & never any cellulose, palm oil or fluff
One-of-a-kind formulas, customized to best support your pet
Proudly supporting pets in need nationwide & using recycled plastic in our packaging
The other guys
No vets in sight
No signs of proven results
Useless fillers with no nutritional value
Copycat formulas you can get anywhere, just marked up
Proudly supporting profits
Frequently Asked Questions
Everything you need to know about the ingredients, quality, and care behind our award-winning treats.
How much should I give my cat each day?
Just one sachet a day — that's the full daily serving. Each box has 30 sachets for a one-month supply. You can offer it straight from the sachet as a lickable treat or spoon it onto her food; most cats look forward to it once it's part of the daily routine. For a stressful event you can see coming — a trip, a vet visit, fireworks — start it a couple of days beforehand.
How soon will I see a difference?
Every cat is different. For a known stressor, starting two to three days ahead gives the calming ingredients time to build. For ongoing tension — a tense multi-cat home, a recent move — give it daily and judge over a couple of weeks. This is gentle, gradual support that takes the edge off, not a switch that flips her calm in an instant, so give it a fair, steady run.
Will it sedate my cat or make her dopey?
No — that's the whole idea. ivvi Relax isn't a sedative; it works with your cat's own calming pathways (the same systems serotonin and GABA use) to help her feel relaxed while staying alert and playful. The goal is calm, not knocked-out — your cat, still herself, just less on edge.
What if my cat is picky and won't eat it?
This is where the creamy, real-tuna formula shines — most fussy cats happily lick it right up, and palatability is the thing owners rave about most. That said, we'll be honest: no single flavor wins over every cat. If yours turns up her nose, our 90-day money-back guarantee means you can try it completely risk-free.
Is it safe? Are there any cautions?
It's a clean, vet-formulated daily supplement, but introduce it gradually so your cat's stomach can adjust. Because the calming active alpha-casozepine comes from a milk protein (casein), use caution if your cat is sensitive to dairy. And because L-tryptophan supports serotonin, always check with your veterinarian first if your cat is pregnant, nursing, or on any medication — especially behavior or anti-anxiety medication.
Can I use it alongside my vet's anxiety plan or medication?
Many owners use it as a gentle, daily, food-based complement to their vet's advice and to environmental steps like pheromone diffusers, safe hiding spots and a predictable routine. Because it's a supplement rather than a medication, it's meant to sit alongside — not replace — a plan your vet has put in place, particularly for a cat with more serious anxiety. Give your veterinarian a quick heads-up, especially if your cat is on any behavior medication, so they can confirm it fits her plan.
What's actually in it, and how clean is it?
A calming blend led by alpha-casozepine (a natural milk-protein peptide) and L-tryptophan, plus chamomile, magnesium, B vitamins, vitamin E and salmon-oil omega-3s — all in a base of real tuna. No meat by-products, no artificial flavors, and no artificial colors, so it's a treat you can feel good about giving her every single day.